|
Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00059178-protein ID=TCONS_00059178-protein|Name=TCONS_00059178-protein|organism=Clytia hemisphaerica|type=polypeptide|length=634bp MWDIEYLPLILENPVPSDISISRSQKPKYIGKLAEELKIQPEEVDYYGKT KAKVGLSILERLKDQKDGKYVVVAGITPTPLGEGKSTTTIGLAQSLSSAL KKQCFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITA ANNLLAAAIDARIFHESTQSDKALFNRLCPKKKGIREFTPIMLRRLKKLG IEKSNPDDLTDEEKGKFARLDFDTSTITWQRVLDTNDRYLRKITVGQSPT EKGRTRECQFDITVASEIMAVLALTTDLRDMRDRLGNMVVASNKEGMPIT ADDLGVGGALTVLMKDAIKPNLMQTLEGSPVFVHAGPFANIAHGNSSILA DKIALKLVGQDGFVVTECGFGADIGMEKFFNIKCRYSGLLPSCVVLVATV RALKMHGGGPKVVAGSPLPEAYTTENIELVEKGFCNLRKQIENALCFGVP VVVAVNKFHTDTDGEINKMISLSKEAGAFDAVLCTHYAEGGQGAVNLSQA VIKASEEKTNFRFLYDLKLPLEEKIEIIAKRIYGADGVSFSDQAKESLAR YTKQGFSELPICMAKTHLSLSDNPELKGAPTGFTLPIRDVRASVGAGFVF PLVGTMSTMPGLPTRPCFYDIDLDPDTEEVQGLM Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
Term | Definition |
GO:0004329 | formate-tetrahydrofolate ligase activity |
GO:0005524 | ATP binding |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
molecular_function |
GO:0005524 |
ATP binding |
molecular_function |
GO:0004329 |
formate-tetrahydrofolate ligase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
IPR000559 | Formate-tetrahydrofolate ligase, FTHFS | PFAM | PF01268 | FTHFS | coord: 17..634 e-value: 5.1E-260 score: 863.3 |
IPR000559 | Formate-tetrahydrofolate ligase, FTHFS | HAMAP | MF_01543 | FTHFS | coord: 15..634 score: 41.599 |
IPR000559 | Formate-tetrahydrofolate ligase, FTHFS | CDD | cd00477 | FTHFS | coord: 32..617 e-value: 0.0 score: 915.39 |
None | No IPR available | GENE3D | 3.40.50.300 | | coord: 305..519 e-value: 4.3E-81 score: 271.7 coord: 27..304 e-value: 6.4E-92 score: 307.2 |
None | No IPR available | GENE3D | 3.10.410.10 | | coord: 521..609 e-value: 6.1E-39 score: 131.5 |
IPR020628 | Formate-tetrahydrofolate ligase, FTHFS, conserved site | PROSITE | PS00722 | FTHFS_2 | coord: 397..408 |
IPR020628 | Formate-tetrahydrofolate ligase, FTHFS, conserved site | PROSITE | PS00721 | FTHFS_1 | coord: 118..128 |
IPR027417 | P-loop containing nucleoside triphosphate hydrolase | SUPERFAMILY | 52540 | P-loop containing nucleoside triphosphate hydrolases | coord: 18..165 coord: 217..627 |
Blast
BLAST of TCONS_00059178-protein vs. Swiss-Prot (Human)
Match: C1TC (C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens GN=MTHFD1 PE=1 SV=3) HSP 1 Score: 957.977 bits (2475), Expect = 0.000e+0 Identity = 477/633 (75.36%), Postives = 541/633 (85.47%), Query Frame = 0 Query: 2 WDIEYLPLILENPVPSDISISRSQKPKYIGKLAEELKIQPEEVDYYGKTKAKVGLSILERLKDQKDGKYVVVAGITPTPLGEGKSTTTIGLAQSLSSALKKQCFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLLAAAIDARIFHESTQSDKALFNRLCPKKKGIREFTPIMLRRLKKLGIEKSNPDDLTDEEKGKFARLDFDTSTITWQRVLDTNDRYLRKITVGQSPTEKGRTRECQFDITVASEIMAVLALTTDLRDMRDRLGNMVVASNKEGMPITADDLGVGGALTVLMKDAIKPNLMQTLEGSPVFVHAGPFANIAHGNSSILADKIALKLVGQDGFVVTECGFGADIGMEKFFNIKCRYSGLLPSCVVLVATVRALKMHGGGPKVVAGSPLPEAYTTENIELVEKGFCNLRKQIENALCFGVPVVVAVNKFHTDTDGEINKMISLSKEAGAFDAVLCTHYAEGGQGAVNLSQAVIKASEEKTNFRFLYDLKLPLEEKIEIIAKRIYGADGVSFSDQAKESLARYTKQGFSELPICMAKTHLSLSDNPELKGAPTGFTLPIRDVRASVGAGFVFPLVGTMSTMPGLPTRPCFYDIDLDPDTEEVQGLM 634
W I+Y L L+ PVPSDI ISRS KPK IGKLA E+ + EEV+ YG+TKAKV LS LERLK + DGKYVVV GITPTPLGEGKSTTTIGL Q+L + L + FACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNL+AAAIDARIFHE TQ+DKALFNRL P G+R F+ I +RRLK+LGIEK++P LTDEE +FARLD D TITWQRVLDTNDR+LRKIT+GQ+PTEKG TR QFDI+VASEIMAVLALTT L DMR+RLG MVVAS+K+G P++A+DLGV GALTVLMKDAIKPNLMQTLEG+PVFVHAGPFANIAHGNSSI+AD+IALKLVG +GFVVTE GFGADIGMEKFFNIKCRYSGL P VVLVATVRALKMHGGGP V AG PLP+AY EN+ELVEKGF NL+KQIENA FG+PVVVAVN F TDT+ E++ + LS+E GAFDAV CTH+AEGG+GA+ L+QAV +A++ ++F+ LYDLKLP+E+KI IIA++IYGAD + +A+ YTKQGF LPICMAKTHLSLS NPE KG PTGF LPIRD+RASVGAGF++PLVGTMSTMPGLPTRPCFYDIDLDP+TE+V GL
Sbjct: 303 WMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPVSAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAFDAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF 935
The following BLAST results are available for this feature:
BLAST of TCONS_00059178-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 ( Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match Name | E-value | Identity | Description | |
C1TC | 0.000e+0 | 75.36 | C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo... | [more] |
back to top
|