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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00049142-protein ID=TCONS_00049142-protein|Name=TCONS_00049142-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1530bp
FQLNSANMAMQRGIPNQQPRFPGMMNQKLPGMQMPNQMQQHRPNMINRMN
NPAMFANSGQTMQMNQQLQQHNQNQNLPQQQQQQLSQNQNNQFQSQPNQQ
PVNNFQMNQQPNSMNNLPSQNLPTSLSNPVKVEDQVMSSCIPTSSTDQIS
TQPSSTPSTLTSSALGLQTPKTETSLLSCNSNVKTEPPSPMQTSTEDVKP
DIKTEVKMEISESTSTSTTTATTSATVSSSSAVVKTEASGSPATVKTEVK
PKVYKIWTKEELIESLMPVFDKVHKIDPESGPFLTPVNPDQLGIPDYFHI
VKNPMDLSTIKSKLDNGDYKDPWGFCDDMRLMFENAWLYNKKTTKVYKYC
SKLYDIFEADIDPVMKKLGYCCGSKHLFNPQVLYCLGQNGSCTIGRDKQY
YSYQDRYHYCENCFNAFEGDSINFGEDTILEKTSNNSNVPKSDFKKKKND
HLDKEPFVECTECKRKMHQVCVLHLDFIWENGFVCDGCRESKSLGERKEN
RFNAKRLPQTKLGEHIEKRVNGYLKTAENSDTAGYVHIRVVSSQNKSVDV
RPGMRDRYSKEGFPESFPYRARALFAFEEIDGVDVCFFGMHTQEFGSDCP
EPNRNRIYLSYLDSVHFFRPRHLKTNVYWEILIGYFEFCKKRGFHWAHIW
SCPPSEGDDYIFHCHPPEQKIPKSKRLVEWYKRMLEKSEKDDVLVEYKDI
YTQAINDLVKSPLNLPYFDGDYWPNQIEDSIREVINEEEERKKNEALQAA
QLAEAENDEEVASEDMVVTSTGKKTKGKRGNKKTTKKNKLNKTPAKKNVT
NNWGSCEVSQRIFTIMEKYKESFFVIRFYKPGEEPTDKIEDPDPLMQSDI
MDGRDAFLTTSRDKHWEFASLRRAKFSSMAMLAELHNQGSDKFVYNCNVC
KRQIITRLHCTVCEDFDLCTICYKDKGHEHKMEKLGLDIETEQPNSANKT
SAINAQEARRKSIERCIESLDHATYCNAKTCNKQACLKMKKVVSHAKNCK
RKTTQGCPICKQLIALCCYHAKSCTRSQCLVPYCQHIKQKLKQQQLQQKL
HQRQILRRRIATMNMPSQAQQQAQAAQKQAQQQAQKQQQAQQQQQQSMQQ
NSQNSSTMNFNPAQQRPMGTPPMQIKQKPINMTSISGTPPPPNVTAKPPP
PVVAPQQTNDINNRNMNMMNPNQPQQPRFAGPNNFPNNNNMQQNNMMNVQ
QQQQNQNNSMMNNMNNFNQQQMNVPPNMSTNQMIPQQNPQNPGMMMNPNM
NTNSQVPMQQLFNAIQNRAGPRGPFHRYGMPPKRPMGMPMSSLQQQKWLQ
QLRFQQQQQQQQQYRQRMALAANMNNVNMNQMSGPGFNNQMTPNQQMNPA
LMGMNRQFSNDAMLPPGQNMVPNNNQTTPQMMAAAANNNRVNQGMNQMMN
QAGIMSPPQQQQMANQMSNPSPRPSMSPSPNLRAPSPHPVMSPQQQAQQQ
HMSPSPAQPLSNQPLTSPAMHSINSPAQQANTPNMDPSSNLQPSSVKSEM
PGSNMSQHQMLDNNPVNEQDDILLQFAESL Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005515 | protein binding |
| GO:0004402 | histone acetyltransferase activity |
| GO:0008270 | zinc ion binding |
| GO:0003712 | transcription cofactor activity |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0016573 | histone acetylation |
| GO:0006355 | regulation of transcription, DNA-templated |
Vocabulary: Cellular Component
| Term | Definition |
|---|
| GO:0005634 | nucleus |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0016573 |
histone acetylation |
| biological_process |
GO:0006355 |
regulation of transcription, DNA-templated |
| cellular_component |
GO:0005634 |
nucleus |
| molecular_function |
GO:0004402 |
histone acetyltransferase activity |
| molecular_function |
GO:0005515 |
protein binding |
| molecular_function |
GO:0003712 |
transcription cofactor activity |
| molecular_function |
GO:0008270 |
zinc ion binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 735..756 |
| None | No IPR available | COILS | Coil | Coil | coord: 1200..1220 |
| None | No IPR available | COILS | Coil | Coil | coord: 1070..1101 |
| None | No IPR available | GENE3D | 1.10.565.10 | | coord: 58..271
e-value: 5.7E-4
score: 18.5 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1..30 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1406..1530 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1065..1151 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 64..127 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 140..241 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 752..798 |
| None | No IPR available | CDD | cd15557 | PHD_CBP_p300 | coord: 457..488
e-value: 7.60372E-14
score: 67.2919 |
| None | No IPR available | CDD | cd02337 | ZZ_CBP | coord: 895..935
e-value: 3.41979E-15
score: 71.4403 |
| None | No IPR available | SUPERFAMILY | 57850 | RING/U-box | coord: 891..937 |
| IPR001487 | Bromodomain | PRINTS | PR00503 | BROMODOMAIN | coord: 278..291
score: 35.56
coord: 328..347
score: 42.07
coord: 310..328
score: 33.75
coord: 294..310
score: 56.01 |
| IPR001487 | Bromodomain | SMART | SM00297 | bromo_6 | coord: 255..366
e-value: 5.6E-37
score: 138.9 |
| IPR001487 | Bromodomain | GENE3D | 1.20.920.10 | | coord: 272..354
e-value: 4.4E-28
score: 97.1 |
| IPR001487 | Bromodomain | PFAM | PF00439 | Bromodomain | coord: 278..351
e-value: 2.1E-19
score: 69.3 |
| IPR001487 | Bromodomain | PROSITE | PS50014 | BROMODOMAIN_2 | coord: 275..347
score: 20.765 |
| IPR001487 | Bromodomain | SUPERFAMILY | 47370 | Bromodomain | coord: 257..371 |
| IPR013178 | Histone acetyltransferase Rtt109/CBP | SMART | SM01250 | KAT11_2 | coord: 520..839
e-value: 1.9E-115
score: 399.5 |
| IPR013178 | Histone acetyltransferase Rtt109/CBP | PFAM | PF08214 | HAT_KAT11 | coord: 529..827
e-value: 1.2E-52
score: 179.3 |
| IPR000197 | Zinc finger, TAZ-type | SMART | SM00551 | TAZ_2 | coord: 957..1035
e-value: 1.8E-20
score: 84.0 |
| IPR000197 | Zinc finger, TAZ-type | GENE3D | 1.20.1020.10 | | coord: 741..933
e-value: 0.071
score: 12.7
coord: 954..1045
e-value: 9.2E-21
score: 73.2 |
| IPR000197 | Zinc finger, TAZ-type | PFAM | PF02135 | zf-TAZ | coord: 963..1034
e-value: 1.9E-9
score: 37.8 |
| IPR000197 | Zinc finger, TAZ-type | PROSITE | PS50134 | ZF_TAZ | coord: 956..1037
score: 15.093 |
| IPR000197 | Zinc finger, TAZ-type | SUPERFAMILY | 57933 | TAZ domain | coord: 956..1039 |
| IPR000433 | Zinc finger, ZZ-type | SMART | SM00291 | zz_5 | coord: 891..932
e-value: 7.9E-9
score: 45.3 |
| IPR000433 | Zinc finger, ZZ-type | PFAM | PF00569 | ZZ | coord: 892..932
e-value: 3.8E-10
score: 39.3 |
| IPR000433 | Zinc finger, ZZ-type | PROSITE | PS01357 | ZF_ZZ_1 | coord: 897..922 |
| IPR000433 | Zinc finger, ZZ-type | PROSITE | PS50135 | ZF_ZZ_2 | coord: 891..934
score: 10.689 |
| IPR010303 | CREB-binding protein/p300, atypical RING domain | PFAM | PF06001 | DUF902 | coord: 364..404
e-value: 8.1E-17
score: 61.3 |
| IPR010303 | CREB-binding protein/p300, atypical RING domain | CDD | cd15802 | RING_CBP-p300 | coord: 378..455
e-value: 1.3457E-22
score: 93.5088 |
| IPR013083 | Zinc finger, RING/FYVE/PHD-type | GENE3D | 3.30.40.10 | | coord: 355..499
e-value: 5.2E-5
score: 22.5 |
| IPR018359 | Bromodomain, conserved site | PROSITE | PS00633 | BROMODOMAIN_1 | coord: 280..339 |
| IPR031162 | CBP/p300-type histone acetyltransferase domain | PROSITE | PS51727 | CBP_P300_HAT | coord: 501..890
score: 91.645 |
Blast
BLAST of TCONS_00049142-protein vs. Swiss-Prot (Human)
Match: EP300 (Histone acetyltransferase p300 OS=Homo sapiens GN=EP300 PE=1 SV=2) HSP 1 Score: 975.696 bits (2521), Expect = 0.000e+0 Identity = 483/923 (52.33%), Postives = 627/923 (67.93%), Query Frame = 0
Query: 143 TSSTDQISTQPSSTPSTLTSSALGLQTPKTETSLLSCNSNVKTEPPSPMQTSTEDVKPDIKTEVKMEISESTSTSTTTATTSATVSSSSAVVKTEASGSPATVKTEVKPKVYKIWTKEELIESLMPVFDKVHKIDPESGPFLTPVNPDQLGIPDYFHIVKNPMDLSTIKSKLDNGDYKDPWGFCDDMRLMFENAWLYNKKTTKVYKYCSKLYDIFEADIDPVMKKLGYCCGSKHLFNPQVLYCLGQNGSCTIGRDKQYYSYQDRYHYCENCFNAFEGDSINFGEDTILEKTSNNSNVPKSDFKKKKNDHLDKEPFVECTECKRKMHQVCVLHLDFIWENGFVCDGCRESKSLGERKENRFNAKRLPQTKLGEHIEKRVNGYLKTAENSDTAGYVHIRVVSSQNKSVDVRPGMRDRYSKEG-FPESFPYRARALFAFEEIDGVDVCFFGMHTQEFGSDCPEPNRNRIYLSYLDSVHFFRPRHLKTNVYWEILIGYFEFCKKRGFHWAHIWSCPPSEGDDYIFHCHPPEQKIPKSKRLVEWYKRMLEKSEKDDVLVEYKDIYTQAINDLVKSPLNLPYFDGDYWPNQIEDSIREVINEEEERKKNEALQAAQLAEAENDEEVASEDMVVTSTGKKTKGKRGNKKTTKKNKLNKTPAKKNVTNNWGSCEVSQRIFTIMEKYKESFFVIRFYK-PGEEPTDKIEDPDPLMQSDIMDGRDAFLTTSRDKHWEFASLRRAKFSSMAMLAELHNQGSDKFVYNCNVCKRQIITRLHCTVCEDFDLCTICYKDKGHEHKMEKLGLDIETEQPNSANKTSAINAQEARRKSIERCIESLDHATYCNAKTCNKQACLKMKKVVSHAKNCKRKTTQGCPICKQLIALCCYHAKSCTRSQCLVPYCQHIKQKLKQQQLQQKLHQRQILRRRIATM 1063
S Q+S PS++ + + S A+ + P E + + ++ + P P T ED+ + KME +E+ ST T + T++S +P K KI+ EEL ++LMP + +++ DPES PF PV+P LGIPDYF IVK+PMDLSTIK KLD G Y++PW + DD+ LMF NAWLYN+KT++VYKYCSKL ++FE +IDPVM+ LGYCCG K F+PQ L C G+ CTI RD YYSYQ+RYH+CE CFN +G+S++ G+D +T+ N K F K+KND LD E FVECTEC RKMHQ+CVLH + IW GFVCDGC + KS RKEN+F+AKRLP T+LG +E RVN +L+ +N +G V +RVV + +K+V+V+PGM+ R+ G ESFPYR +ALFAFEEIDGVD+CFFGMH QE+GSDCP PN+ R+Y+SYLDSVHFFRP+ L+T VY EILIGY E+ KK G+ HIW+CPPSEGDDYIFHCHPP+QKIPK KRL EWYK+ML+K+ + ++ +YKDI+ QA D + S LPYF+GD+WPN +E+SI+E+ EEEERK+ E + D + A + ++ K+ RGNK K P NV+N ++SQ+++ MEK+KE FFVIR P I DPDPL+ D+MDGRDAFLT +RDKH EF+SLRRA++S+M ML ELH Q D+FVY CN CK + TR HCTVCED+DLC CY K H+HKMEKLGL ++ E N+ + + ++RR SI+RCI+SL HA C C+ +C KMK+VV H K CKRKT GCPICKQLIALCCYHAK C ++C VP+C +IKQKL+QQQLQ +L Q Q+LRRR+A+M
Sbjct: 945 VSIEGQVSNPPSTSSTEVNSQAIAEKQPSQEVKM---EAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKK-------KIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQ-LCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTIN----KEQFSKRKNDTLDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLK-KSARTRKENKFSAKRLPSTRLGTFLENRVNDFLRR-QNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTSNESTDVTKGDSKNAKKKNNKKTSKNKSSLSRGNK---------KKPGMPNVSN-----DLSQKLYATMEKHKEVFFVIRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDES-NNQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASM 1835
The following BLAST results are available for this feature:
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