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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00049928-protein ID=TCONS_00049928-protein|Name=TCONS_00049928-protein|organism=Clytia hemisphaerica|type=polypeptide|length=820bp
MFYSNDSLYFYHGKLSRDQASQILLRHGNGKDGYYLIRDCSRSPGDYVLS
IWIRNQVMHFQVQCFGDNRFAIDDGPVFQGLDSLTAHYSVSPDGLPYKLT
GFAVGQLPPLKSLKFGVDTNLHSACQKRSISTVKQLLQDPKVRSDIDGRS
SKGQTALHISCLNGDSDIVATLLYAKANTSAADNTGKTPVQVTCMAGHAQ
TLRVLIMQGNADFHERNTLNGWVPLHEVCMRGFMDCVKILLSFQASMHPR
TSDGDTPRDLAIRYGHSEVEEFLDNYPVPAPKTTPMQWLHQNLDRNAAVN
VLESNGLINGSFLIRNSIKCHGYYVLSLVCEKKVFHFQIQSRADRWFYID
DGPLFETLPHLVDHYLQYADGLPCVIKIPVPSPENRNLTKRSPLPPPPAQ
GHPQSPLPGNPSGNPVSPLVLPSRPPRPSTRKDLPSPIPRQGSRDDEFQH
QRPHPPLDQRPSKGGPPVPASRPSVKGSPLPETPASPQHTPQSHPQFPPS
QQHPPPQPLNKPKVASPKASVKAKAKSPAQQANNAQQTVIQKDSLELGQE
LGVGEFGSVLKGVWKSPSGEKISVALKTLHKDKLLQGEKEFLREARVMSQ
LDHPCIVRLLGVCLGPPMILVQELVTMGALLDHLIDHQDDIGEIDLKLWA
AQIAWGMMYLEQKRFVHRDLATRNILLYNKSQAKISDFGLSRAVGAGSDY
YQAQQGGRWPVKWYSPESINYGTFSQKSDVWSYGVTLWEMFTFGELPYGE
MTGAEVISLLEQGQRLERPEDCPQHTYSIMLRCWHIDPAQRPTFKELHTI
FSTDPEYEDARKYRERLKKK Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004672 | protein kinase activity |
| GO:0005515 | protein binding |
| GO:0004713 | protein tyrosine kinase activity |
| GO:0005524 | ATP binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0005515 |
protein binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
| molecular_function |
GO:0004713 |
protein tyrosine kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR000980 | SH2 domain | PRINTS | PR00401 | SH2DOMAIN | coord: 10..24
score: 37.2
coord: 333..343
score: 30.75
coord: 32..42
score: 34.85
coord: 354..368
score: 37.98 |
| IPR000980 | SH2 domain | SMART | SM00252 | SH2_5 | coord: 8..94
e-value: 1.9E-25
score: 100.5
coord: 286..371
e-value: 9.1E-26
score: 101.6 |
| IPR000980 | SH2 domain | PFAM | PF00017 | SH2 | coord: 288..365
e-value: 5.0E-16
score: 58.5
coord: 10..88
e-value: 5.1E-17
score: 61.6 |
| IPR000980 | SH2 domain | GENE3D | 3.30.505.10 | | coord: 276..393
e-value: 5.8E-28
score: 96.5
coord: 2..108
e-value: 4.2E-24
score: 84.0 |
| IPR000980 | SH2 domain | PROSITE | PS50001 | SH2 | coord: 10..103
score: 17.775 |
| IPR000980 | SH2 domain | PROSITE | PS50001 | SH2 | coord: 288..380
score: 18.235 |
| IPR000980 | SH2 domain | SUPERFAMILY | 55550 | SH2 domain | coord: 266..381 |
| IPR000980 | SH2 domain | SUPERFAMILY | 55550 | SH2 domain | coord: 7..106 |
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PRINTS | PR00109 | TYRKINASE | coord: 728..750
score: 57.24
coord: 622..635
score: 35.76
coord: 709..719
score: 51.89
coord: 772..794
score: 47.39
coord: 659..677
score: 59.69 |
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PFAM | PF07714 | Pkinase_Tyr | coord: 545..799
e-value: 1.0E-89
score: 300.1 |
| IPR002110 | Ankyrin repeat | SMART | SM00248 | ANK_2a | coord: 116..148
e-value: 740.0
score: 6.0
coord: 253..282
e-value: 1300.0
score: 4.1
coord: 152..181
e-value: 0.0081
score: 25.4
coord: 185..215
e-value: 8.7
score: 15.3
coord: 220..249
e-value: 0.084
score: 22.0 |
| IPR002110 | Ankyrin repeat | PROSITE | PS50088 | ANK_REPEAT | coord: 152..184
score: 11.274 |
| IPR002110 | Ankyrin repeat | PROSITE | PS50088 | ANK_REPEAT | coord: 220..252
score: 8.79 |
| IPR020635 | Tyrosine-protein kinase, catalytic domain | SMART | SM00219 | tyrkin_6 | coord: 545..801
e-value: 4.4E-137
score: 471.4 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 631..820
e-value: 9.0E-49
score: 165.5 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 523..630
e-value: 2.8E-22
score: 78.3 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 383..537 |
| None | No IPR available | CDD | cd00204 | ANK | coord: 147..273
e-value: 1.41867E-28
score: 110.936 |
| None | No IPR available | CDD | cd05060 | PTKc_Syk_like | coord: 550..806
e-value: 7.58113E-163
score: 475.301 |
| None | No IPR available | CDD | cd10348 | SH2_Cterm_shark_like | coord: 287..372
e-value: 1.1293E-42
score: 149.495 |
| IPR020683 | Ankyrin repeat-containing domain | GENE3D | 1.25.40.20 | | coord: 195..275
e-value: 2.6E-17
score: 62.3 |
| IPR020683 | Ankyrin repeat-containing domain | GENE3D | 1.25.40.20 | | coord: 111..194
e-value: 1.2E-17
score: 63.2 |
| IPR020683 | Ankyrin repeat-containing domain | PFAM | PF12796 | Ank_2 | coord: 121..216
e-value: 2.6E-12
score: 47.0 |
| IPR020683 | Ankyrin repeat-containing domain | PROSITE | PS50297 | ANK_REP_REGION | coord: 116..273
score: 30.502 |
| IPR020683 | Ankyrin repeat-containing domain | SUPERFAMILY | 48403 | Ankyrin repeat | coord: 119..275 |
| IPR008266 | Tyrosine-protein kinase, active site | PROSITE | PS00109 | PROTEIN_KINASE_TYR | coord: 665..677 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 551..577 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 545..801
score: 39.326 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 536..801 |
Blast
BLAST of TCONS_00049928-protein vs. Swiss-Prot (Human)
Match: KSYK (Tyrosine-protein kinase SYK OS=Homo sapiens GN=SYK PE=1 SV=1) HSP 1 Score: 267.314 bits (682), Expect = 5.120e-79 Identity = 177/517 (34.24%), Postives = 250/517 (48.36%), Query Frame = 0
Query: 286 MQWLHQNLDRNAAVNVLESNGLINGSFLIRNSIKCHGYYVLSLVCEKKVFHFQIQSRADRWFYIDDGPLFETLPHLVDHYLQYADGLPCVIKIP---VPSPENRNLTKRSPLPPPPAQGHPQSPLPGNPSGNPVSPLVLPSRPPRPSTRKDLPSPIPRQGSRDDEFQHQRPHPPLDQRPSKGGPPVPASRPSVKGSPLPETPASPQHTPQSHPQFPPSQQHPPPQPLNKPKVASPKASVKAKAKSPAQQANNAQQTVIQKDSLEL-GQELGVGEFGSVLKGVWK--SPSGEKISVALKTLHKDKLLQGEKEFLREARVMSQLDHPCIVRLLGVCLGPPMILVQELVTMGALLDHLID--HQDDIGEIDLKLWAAQIAWGMMYLEQKRFVHRDLATRNILLYNKSQAKISDFGLSRAVGAGSDYYQAQQGGRWPVKWYSPESINYGTFSQKSDVWSYGVTLWEMFTFGELPYGEMTGAEVISLLEQGQRLERPEDCPQHTYSIMLRCWHIDPAQRPTF 794
M W H + R + ++ NG FLIR + +G Y L L+ E KV H++I I +G F+TL LV+HY ADGL V+ +P + + N N R LP P S + + P+P RK P+ QG+R + S + P P+ P + + P + P + + A P+ ++ K + + + L L +ELG G FG+V KG ++ LK D L+ E L EA VM QLD+P IVR++G+C +LV E+ +G L +L H D I+L Q++ GM YLE+ FVHRDLA RN+LL + AKISDFGLS+A+ A +YY+AQ G+WPVKWY+PE INY FS KSDVWS+GV +WE F++G+ PY M G+EV ++LE+G+R+ P CP+ Y +M CW D RP F
Sbjct: 166 MPWFHGKISREESEQIVLIGSKTNGKFLIR-ARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLP---------GSHPATWSAGGIISRIKSYSFPKPGHRKSSPA----QGNRQE-------------------------------STVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPE-EIRPK------------EVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALK--DELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIEL---VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619
The following BLAST results are available for this feature:
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