TCONS_00050129-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00050129-protein
Unique NameTCONS_00050129-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1023

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00050129-protein ID=TCONS_00050129-protein|Name=TCONS_00050129-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1023bp
MRLLHFWKAFNIRPRSFQKAIVNDSTNFHRKMATFSSMEAVSGEYKHLNG
IFKNVLESSTDNLEFFNQKQKQDFHSSFQNIINVLDPLQMSLGVITNCCS
KFDASPTSKGNGYRSIISIIESCLIKIQELSRHIQRSREKIFFRSYHVYM
ELESYSQVLTRLLTISHLAIVLLDYSDVGNLFPHDCVVDDMMIDFEKINR
ECFYGRSFGFQYSDSIRQSLHVIAVAMAAYGDGYQQHNHSLTRALSSMLH
SGKYMVNPELRAQRINELTQNANIDFCKAFWGLTEEYGVQHAPLLICPAM
AVNLEFEIPPQQLGVQTVDKQNEVTVDFPFLNSGYTGIPCRLLSYVLRSG
QDSLNKAGSASSSGVSPLGPKPAQKSRYLMIHCHGGGFVAQSSKSHEMYL
RYMAKELQIPILSIDYSLAPDAPYPQAVKEVYYAYVWALNNFDKLGTLGE
KIVFAGDSAGANIVTAITIQAIKDNIRLPDSIVVAYPPYRLQFLPSPSRI
LCLMDPLLPVGVLKSCIQAYTGGFKHVASNTNMFTFDPSSYNAFDLDFGE
EDNRGFLSKKHLQHSYSETQLNVIKAKYNNEFEESSSFMQENESFCSEFP
VYDSEGDILNTESAEDTKSDVAEDDFLYFKSSTAHAQDGGTSDEDKKSTG
SASLLQSLSDQVSSKVQGLTTSISGYFLSNLPTSESNKNNNECSSKQTQE
QTGVIKNRKKSLELNLDLGNQNSMNKNSTKDNGKSSFTICRECLFRSEQC
ICHLSPKALRRRAEKYTEHYKFSHHHVLNSPRRVRSSSLTHREHSGKEHS
KVHRIRSVTHCNPQEIGLNIDTDEGALCSPTAKDKALQNFRLSLLGSSTE
TPPASPSTQRTQSSAPSPRVVYDSTTESCVILTPEEEGQVHTEGELGGGG
ETKDMLGATSKAFNDAKDPLMSPFLADDETLKCMPPITIVASALDPLLDD
SVEFVRKLQKLEKPSELYILEKLPHGFLNFQPFSTEAREGCDLIIACVKK
SLHMGMRRLDSTQSFGFPAKDSP
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031734XLOC_031734Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00050129TCONS_00050129Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013094AB_hydrolase_3
IPR029058AB_hydrolase
IPR010468HSL_N
IPR033140Lipase_GDXG_put_SER_AS
Vocabulary: Molecular Function
TermDefinition
GO:0016787hydrolase activity
GO:0016298lipase activity
Vocabulary: Biological Process
TermDefinition
GO:0008152metabolic process
GO:0016042lipid catabolic process
GO:0008203cholesterol metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008203 cholesterol metabolic process
biological_process GO:0016042 lipid catabolic process
biological_process GO:0008152 metabolic process
molecular_function GO:0016787 hydrolase activity
molecular_function GO:0016298 lipase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013094Alpha/beta hydrolase fold-3PFAMPF07859Abhydrolase_3coord: 380..522
e-value: 1.9E-28
score: 99.7
coord: 913..978
e-value: 8.1E-9
score: 35.5
IPR029058Alpha/Beta hydrolase foldGENE3D3.40.50.1820coord: 364..693
e-value: 4.2E-26
score: 91.1
IPR029058Alpha/Beta hydrolase foldGENE3D3.40.50.1820coord: 837..1012
e-value: 7.6E-14
score: 51.0
IPR029058Alpha/Beta hydrolase foldSUPERFAMILY53474alpha/beta-Hydrolasescoord: 908..1000
IPR029058Alpha/Beta hydrolase foldSUPERFAMILY53474alpha/beta-Hydrolasescoord: 374..533
IPR010468Hormone-sensitive lipase, N-terminalPFAMPF06350HSL_Ncoord: 52..351
e-value: 1.3E-86
score: 290.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 680..707
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 633..652
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 846..870
IPR033140Lipase, GDXG, putative serine active sitePROSITEPS01174LIPASE_GDXG_SERcoord: 452..464

Blast
BLAST of TCONS_00050129-protein vs. Swiss-Prot (Human)
Match: LIPS (Hormone-sensitive lipase OS=Homo sapiens GN=LIPE PE=1 SV=4)

HSP 1 Score: 348.206 bits (892), Expect = 2.422e-103
Identity = 183/496 (36.90%), Postives = 285/496 (57.46%), Query Frame = 0
Query:   48 LNGIFKNVLESSTDNLEFFNQK----QKQDFHSSFQNIINVLDPLQMSLGVITNCCSKFDASPTSKGNGYRSIISIIESCLIKIQELSRHIQRSREKIFFRSYHVYMELESYSQVLTRLLTISHLAIVLLDYSDVGNLF--PHDCVVDDMMIDFEKINRECFYGRSFGFQYSDSIRQSLHVIAVAMAAYGDGYQQHNHSLTRALSSMLHSGKYMVNPELRAQRINELTQNANIDFCKAFWGLTEEYGVQHAPLLICPAMAVNLEFEIPPQQLGVQ-TVDKQNEVTVDFPFLNSGYTGIPCRLLSYVLRSGQDSLNKAGSASSSGVSPL--GPKPAQ--KSRYLMIHCHGGGFVAQSSKSHEMYLRYMAKELQIPILSIDYSLAPDAPYPQAVKEVYYAYVWALNNFDKLGTLGEKIVFAGDSAGANIVTAITIQAIKDNIRLPDSIVVAYPPYRLQFLPSPSRILCLMDPLLPVGVLKSCIQAYTGGFKHVASNTN 532
            L  + ++++  + DN+ FF+ +      Q     F  +      L+ +LG +      FD  P +  NGYRS++     CL  +   SR++  +R  IFFR+ H   ELE+Y   LT+L  + + A  LL  +  G LF    + +  D + ++  +++ CFYGR  GFQ++ +IR  L  I++ + ++G+ Y+++   L+ A SS+  SG++ ++PELR      +TQN ++ F KAFW +TE   +     +    + V+    +PP+   +  T D    VT+  P  ++G   +  RL+SY LR GQDS   +    S+G   L   P+P Q  +SR L++H HGGGFVAQ+S+SHE YL+  A+EL  PI+SIDYSLAP+AP+P+A++E ++AY WA+ +   LG+ GE+I  AGDSAG N+   + ++A    +R+PD I+ AYP   LQ   SPSR+L LMDPLLP+ VL  C+ AY G      SN++
Sbjct:  304 LRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGAEFERITQNLDVHFWKAFWNITEMEVLSSLANMASATVRVSRLLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGPVLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTSRSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVLSKCVSAYAGAKTEDHSNSD 799          

HSP 2 Score: 88.9669 bits (219), Expect = 8.339e-18
Identity = 39/83 (46.99%), Postives = 53/83 (63.86%), Query Frame = 0
Query:  917 KDPLMSPFLADDETLKCMPPITIVASALDPLLDDSVEFVRKLQKLEKPSELYILEKLPHGFLNFQPFSTEAREGCDLIIACVK 999
            K+P MSP LA D  LK +PP+ IVA ALDP+LDDSV   R+L+ L +P  L ++E LPHGFL       E R+  +L +  ++
Sbjct:  966 KNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLTLAALCRETRQAAELCVERIR 1048          
The following BLAST results are available for this feature:
BLAST of TCONS_00050129-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
LIPS2.422e-10336.90Hormone-sensitive lipase OS=Homo sapiens GN=LIPE P... [more]
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