TCONS_00057319-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00057319-protein
Unique NameTCONS_00057319-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1490

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00057319-protein ID=TCONS_00057319-protein|Name=TCONS_00057319-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1490bp
MIPMDNENAFFENKVKEIINQELVKAKFDDLCKTISTKIIERVHKIDDDH
QEINQQYDELGEMIEGLLANNPELKDVVSKSKDSVIVIDDDEEDDNLKEN
TKTNYKNGETTNCKNTLVKEISKSISLSISKETNTTAKSYSTVLNSSRKL
EDVISKLTSRVKNSSSITDRVSTDDSQPDETTDQSSQEECDDPITISESN
ELPSIVTTTTLTSQSINSILNSPSKIDNETSVENEGSEIEIGKTKNIDLP
ASLLQTLQKVEDSGTNEPIVVQESPVKTNSSVNEQPTKTFTENRNLLIKS
KKEKNSGTLSDNDKTNLLTYTLETNTNKRDKIVSLNIVSSSKDQYNLKVE
PSVTPGRSSPRSPRTKSVKNKLELSIDTDTFIPTIPLPPRRHEFAFEYEK
LVFAKPGKSDIWYQAKLMKELGAKGPSAKYSIQFISGQKLRQKVDSKSIA
TRQHCHPSDVVLGTRIVAGRPSDTVNSTVQKKYKDITTTTSYTVMFAGTI
AELACEANRYRYLVFFDDGYAQYLPLNRIFPVVHSSKNVWEDVSPDCQEF
IKEYLQEYPMRPLVVTQLGYEMQTEWNGEWWQSKVVSIDSSLVKILFDVD
KRSEWIYRGTTRLEPLYNHFINPPAPESKASKGKKGRKKGAKETLVSYVD
EKITDPQHGVCNHSLTDPRGEKQFAEWGEPRDFTDKILARCYNEEGVSLS
LTSPRVSSPPPAPPVDHKMLKIVTQSTEGAQNATRGHLKLKLKRSSSNDL
FKASKSSSPSNSPRCRKKLKAESPDDYADNNLPFDGQMQLSPSPEKSKEE
ISQEELLGALSALNTSPNVLSPKTKGESSATPETTKATPRGGRSPRRSST
KPSPQTPNFPKPTRHTCNENCITDRRNILDYHRFGFTNYLSIPFHLGWKR
ESAKKSSSYHRDIYYRTPCNKRVRNLAEITKYLLMTNCTNVCIDMFCFYS
KISCRSQPVKAKTPKVKIDDLSDGRETCPVVLINDINEDLPPHLAYISSR
NKAEDVYINIDPGFLVCCDCTDFCQDKSKCRCAQLTVESSNAIDGVVDPN
AGYHYRRLKECITTGIYECNSNCSCKKSCYNRVVQNGIQLRLQVFMTENR
GWGLRCMDDVAKGTFICTYAGQVLNEQTANREGMDYGDEYLAELDHIEVV
ERAKDGYESDVPELKEKSFEDSDNESSIYTESESSDSVINISSDSDGDSS
DERDGEVGTIEPLPKKLRSATSIDAQTSTAKIKDTSKDEKQSQSADTAIN
KKTTEKNKGEDPKSSEFQNDKTKTSDSSETRTSKTTVDEPMEQTNKKSEN
PTTADKKSETLESGKPEAMASSATAPAALPQGKKARLAKKSTGQFACKGT
NNGIIIGQKKTKDKEKDGKEPETGETKTSNDTNDTSTVKKDKVIPTRSLF
NKDDQMYVIDAKSFGNVGRFMNHSCSPNLFVQNVMVDTHDLRFPWVAFFA
GQNIPAYTELTWDYSYEIGSVSGKELYCKCGSKDCKGRLL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_036121XLOC_036121Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00057319TCONS_00057319Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001214SET_dom
IPR001739Methyl_CpG_DNA-bd
IPR007728Pre-SET_dom
IPR003616Post-SET_dom
IPR016177DNA-bd_dom
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0003677DNA binding
GO:0018024histone-lysine N-methyltransferase activity
GO:0008270zinc ion binding
Vocabulary: Cellular Component
TermDefinition
GO:0005634nucleus
Vocabulary: Biological Process
TermDefinition
GO:0034968histone lysine methylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0034968 histone lysine methylation
cellular_component GO:0005634 nucleus
molecular_function GO:0003677 DNA binding
molecular_function GO:0018024 histone-lysine N-methyltransferase activity
molecular_function GO:0005515 protein binding
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1147..1167
NoneNo IPR availableCOILSCoilCoilcoord: 50..70
NoneNo IPR availableGENE3D3.30.890.10coord: 891..952
e-value: 2.7E-10
score: 39.7
NoneNo IPR availableGENE3D2.170.270.10coord: 955..1490
e-value: 2.8E-69
score: 233.1
NoneNo IPR availableGENE3D2.30.30.140coord: 462..529
e-value: 4.5E-7
score: 29.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 348..370
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1357..1390
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 744..867
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1156..1337
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 164..203
NoneNo IPR availableCDDcd00122MBDcoord: 890..948
e-value: 8.97079E-12
score: 61.9565
NoneNo IPR availableSUPERFAMILY82199SET domaincoord: 1403..1480
coord: 962..1148
IPR001214SET domainSMARTSM00317set_7coord: 1090..1471
e-value: 9.6E-38
score: 141.4
IPR001214SET domainPFAMPF00856SETcoord: 1101..1464
e-value: 2.7E-22
score: 79.8
IPR001214SET domainPROSITEPS50280SETcoord: 1090..1465
score: 17.134
IPR001739Methyl-CpG DNA bindingSMARTSM00391TAM_2coord: 887..960
e-value: 1.0E-6
score: 38.3
IPR001739Methyl-CpG DNA bindingPFAMPF01429MBDcoord: 894..953
e-value: 1.1E-6
score: 28.2
IPR001739Methyl-CpG DNA bindingPROSITEPS50982MBDcoord: 884..953
score: 11.394
IPR007728Pre-SET domainSMARTSM00468preset_2coord: 968..1074
e-value: 5.9E-15
score: 65.7
IPR007728Pre-SET domainPFAMPF05033Pre-SETcoord: 972..1082
e-value: 1.1E-12
score: 48.5
IPR007728Pre-SET domainPROSITEPS50867PRE_SETcoord: 1016..1087
score: 10.338
IPR003616Post-SET domainPROSITEPS50868POST_SETcoord: 1474..1490
score: 8.79
IPR016177DNA-binding domainSUPERFAMILY54171DNA-binding domaincoord: 891..974

Blast
BLAST of TCONS_00057319-protein vs. Swiss-Prot (Human)
Match: SETB1 (Histone-lysine N-methyltransferase SETDB1 OS=Homo sapiens GN=SETDB1 PE=1 SV=1)

HSP 1 Score: 287.345 bits (734), Expect = 3.666e-79
Identity = 147/375 (39.20%), Postives = 217/375 (57.87%), Query Frame = 0
Query:  853 SPQTPNFPKPTR------HTCNENCITDRRNILDYHRFGFTNYLSIPFHLGWKRESAKK----SSSYHRDIYYRTPCNKRVRNLAEITKYLLMTNCTNVCIDMFCF--YSKISCRSQPVKAKTPKVKIDDLSDGRETCPVVLINDINEDLPPHLAYISSRNKAEDVYINIDPGFLVCCDCTDFCQDKSKCRCAQLTVESSNAI-DGVVDPNAGYHYRRLKECITTGIYECNSNCSCKKS-CYNRVVQNGIQLRLQVFMTENRGWGLRCMDDVAKGTFICTYAGQVLNEQTANREGMDYGDEYLAELDHIEVVERAKDGYESDVPELKEKSFEDSDNESSIYTESESSDSVINISSDSDG-DSSDERDGEVGTIEP 1212
            +P  P++  P        H C+  C++  R + +    G  N L +P    ++R +A++       +H  + Y+TPC   +R + EI +YL  T C  + ++MFC   Y  +  + QP K   P   I D++ G+E  P+  +N+I+   PP +AY   R   + V+IN  P FLV CDC D C+DKSKC C QLT++++     G ++PN+GY Y+RL+EC+ TG+YECN  C C  + C NR+VQ+G+Q+RLQ+F T+N+GWG+RC+DD+AKG+F+C YAG++L +  A++EG++ GDEY A LDHIE VE  K+GYESD P                             SSDS G D  D+ DG  GT +P
Sbjct:  558 APAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRG-KNPLLVPLLYDFRRMTARRRVNRKMGFH--VIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYK---PFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAP----------------------------CSSDSSGVDLKDQEDGNSGTEDP 898          

HSP 2 Score: 160.999 bits (406), Expect = 1.329e-39
Identity = 79/212 (37.26%), Postives = 123/212 (58.02%), Query Frame = 0
Query:  408 KSDIWYQAKLMKELGAKGPSAKYSIQFISGQKLRQKVDSKSIATRQHCHPSDVVLGTRIVAGRPSDTVNSTVQKKYKDITTTTSYTVMFAGTIAELACEANRYRYLVFFDDGYAQYLPLNRIFPVVHSSKNVWEDVSP-DCQEFIKEYLQEYPMRPLVVTQLGYEMQTEWNGEWWQSKVVSIDSSLVKILFDVDKRSEWIYRGTTRLEPLYN 618
            ++  W++  L+  +   GP  KY ++F    K +  +    IA   H     + +G+R+VA             KYKD     +   ++AG +AE     N+ R+L+FFDDGYA Y+  + ++P+    K  WED+    C++FI+EY+  YP RP+V+ + G  ++TEW G WW+S+V  +D SLV+ILF  DKR EWIYRG+TRLEP+++
Sbjct:  209 RTKTWHKGTLIA-IQTVGPGKKYKVKF--DNKGKSLLSGNHIAYDYHPPADKLYVGSRVVA-------------KYKD----GNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFS 400          

HSP 3 Score: 160.229 bits (404), Expect = 1.984e-39
Identity = 83/157 (52.87%), Postives = 105/157 (66.88%), Query Frame = 0
Query: 1334 KARLAKKSTGQFACKGTNNGIIIGQKKTKDKEKDGKEPETGETKTSNDTNDTSTVKKDKVIPTRSLFNKDDQMYVIDAKSFGNVGRFMNHSCSPNLFVQNVMVDTHDLRFPWVAFFAGQNIPAYTELTWDYSYEIGSVSGKELYCKCGSKDCKGRLL 1490
            K ++A KST  FA K T+ GI I  K T                 S D  +++ V+K+    TR  ++ ++  Y+IDAK  GN+GR++NHSCSPNLFVQNV VDTHDLRFPWVAFFA + I A TELTWDY+YE+GSV GKEL C CG+ +C+GRLL
Sbjct: 1156 KRQVAVKSTRGFALKSTH-GIAI--KST--------------NMASVDKGESAPVRKN----TRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1291          
The following BLAST results are available for this feature:
BLAST of TCONS_00057319-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
SETB13.666e-7939.20Histone-lysine N-methyltransferase SETDB1 OS=Homo ... [more]
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