TCONS_00062325-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00062325-protein vs. Swiss-Prot (Human)
Match: DPOE1 (DNA polymerase epsilon catalytic subunit A OS=Homo sapiens GN=POLE PE=1 SV=5)

HSP 1 Score: 2607.4 bits (6757), Expect = 0.000e+0
Identity = 1265/2199 (57.53%), Postives = 1629/2199 (74.08%), Query Frame = 0

Query:    1 GSERELATFLNKKFSGMIAGIEMLDKEDLDLHNHLTGLKKTYVKLSFHNVKELLKIKGQLMPIVRKNKEREKA-NATVALVT------GESSKAPSSSK--SDQMDNILDIREYDVPYYVRVSIDTKISVGHWYTVKVRGITH-VEITERTDLLHRPDPVVMAFDIETTKLPLKFPDSAIDSIMMISYMIDGQGYLITNREIISEDIEDFEYTPRPEYEGPIIVFNEPDEAALLRRWFDHITETKPMIYVTYNGDFFDWPFIDARAKIHGIDMKDETGFAPDAQKEYKSSYGIHMDAFRWVQRDSYLPVGSQNLKAVTKAKLRYNPVEVDPEEMVRMASEEPTEMANYSVSDAVATYYLYMQYVHPFIFALCTIIPMDPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQIHTKFFE-GHLLDTETYVGGHVEALESGVFRSDIASRFRMVPEAFQGLIDNIHDTIKTTVENEEGVPIEFVTNMDEVCEDVVKQLEELRDTPNRLEKPMIYHLDVAAMYPNIILTNRLQPPAQVNEVTCAACDFNKPGAKCQRKLTWMWRGDYSPANYSEYQNIRSQLEVEKMPGRFPGDPPRNFHQLWPAEQSLQEKKRLADYSHKAYKKTKITKSELRSTVICQRENSFYIDTVRAFRDRRYEYKGLLKVWKKKVSAAVDKGDPAEVKHAKGMEVLYDSLQLAHKCILNSFYGYVMRKGSRWFSMEMAGIVCYTGANIITQARELVEQIGRPLELDTDGIWCILPASFPENFLVKTTHPKKPKITISYPGAMLNYIVQTNFTNDQYHNLKNAEKLDYEIRKENSIFFEVDGPYKAMILPAAKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLQGTSLETCYAAVAKIADYWLDVLYTKGENLPDSELFELISENRSMSKALEEYGSQKSTSISTAKRLAEFLGDQMVKDKGLACRFVISRRPEGAPVTERAIPLAIFQTEESIKKHYLKKWLKVPANFDFDIRNILDWNYYIERLNSCIQKIVTIPAALQGVSNPVPRCQHPDWLRKRLLEKNDSFQQQRITDMFTKLKKKKAAEPPKNADPDVQVIEESND-----IADIEEIGGASAGKRAHTTPPAPTVTKKRKVDKHVENTEFVESDLLKS--WKEVLGNPPSMGTTKDEQEAWVTFHKRKWTLQRLQRAAARESRRQLRKEGVNVEHHRRALPQSGLDNFFQKQARTILESTWEIIQVSESAVPGVFNVFSMINNDLHNIKVNIPRIFYVNSKKLKEGHGATWRKVNKILPRSYPSMHLYQYAVPEAIFREHSSELVADLSSPDVEGIYETQVPLDVRAVIKLGCVCRVHRNVARALNGRDVDNFNLDQLEFKTLAGNTYLETDKLKHIYFYHGQLDNRAIYALFMPASQKVSVFVLNTVKSNQMPNLSNLYKNERSNRILEMEEMGRAYTPPDVSSYSFDVRVETDTRLLYRDIQRALSAYRDEKRGPTLVMLQTQSDQAHWKANIPELDNFPLVEMPSVEIDTDQLNALDWQRQFAKKFIQAYLGVNDWLQAQLDQARYFHIPVGNIPPNDPFLYASDIFFARHLSRSNHVLWISPTDRPDLGGKEEDNFRLVTEFDEGGSPEINQPGCYSTVCVEISIDSLAVNTVLQSHHVHDAEGVAS---SLDTIQQASLEEMLNSRSGAAATLTSYDEAASCAQSFKVLKGLIISWIQEVFANRNDFADTQLIHFYRYLRSPEAMLYDPALCKYIHGLMKKFFMQLIAEFKTLGSTIVYANFNKIILNSKKRRVKDALAYVQYILTSIRSKPLFKNIALEPRSCWEYLMWMDPANHGGIRAKEIPENFMSNVDDEEKEENGNEFDSDDDEDIRDLVAHAK-------EQKVEMNWNLEKFLPTSAACQTFFKVCIADHIHSVYVHIVEQLQTHKGGSTPVKRRGLST-QQEMMAETTTTPSTVEFAQSRIQDVLTEQLFGITQKIHKTLSGGRGKDAGLE-FPVLAGSHLPLKNPSLEFIKAVCQVLQLDVNIRNQVNKLRRDLLKLVGIGQFADEANFQDPCLSFIVPEMICEYCNSCRDLDLCRDPLITPAKGNQPASVRCDNPDCQQQYNMSLVEEQLVLMLSRRAMSYTLQDLKCLKCKMVKDKNMSKFCECAGRFGNLTSPDDFKKQLKIFGNIAKHYQMSHLQETLDFM 2169
            G ERE+++FL+KKF G IA +E + KEDLDL NHL GLK+ Y++LSFH V++L+K++ ++ P V+KN+E++ A +A  AL++      G  +    +SK  +DQ+DNI+D+REYDVPY++R+SID KI V HWY V+ RG    VEIT R DL+ RPDPVV+AFDIETTKLPLKFPD+  D IMMISYMIDGQGYLITNREI+SEDIEDFE+TP+PEYEGP  VFNEPDEA L++RWF+H+ ETKP I VTYNGDFFDWPF++ARA +HG+ M+ E GF  D+Q EYK+   IHMD  RWV+RDSYLPVGS NLKA  KAKL Y+PVE+DPE+M RMA+E+P  +A YSVSDAVATYYLYM+YVHPFIFALCTIIPM+PDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQ   K  + GH+LD+ETYVGGHVEALESGVFRSDI  RFRM P AF  L+  +  T++  +E EE VP+E VTN +EVC+++  +L  L+D P+R+E P+IYHLDV AMYPNIILTNRLQP A V+E TCAACDFNKPGA CQRK+ W WRG++ PA+ SEY  I+ QLE EK P  FP  P R FH+L   EQ+  EK+RLADY  KAYKK  ITK E R T ICQRENSFY+DTVRAFRDRRYE+KGL KVWKKK+SAAV+ GD AEVK  K MEVLYDSLQLAHKCILNSFYGYVMRKG+RW+SMEMAGIVC+TGANIITQAREL+EQIGRPLELDTDGIWC+LP SFPENF+ KTT+ KKPK+TISYPGAMLN +V+  FTNDQY  L     L Y  R ENSIFFEVDGPY AMILPA+KEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFL+G++LE  Y +VAK+ADYWLDVLY+K  N+PDSELFELISENRSMS+ LE+YG QKSTSISTAKRLAEFLGDQMVKD GL+CR++ISR+PEG+PVTERAIPLAIFQ E +++KH+L+KWLK  +  DFDIR ILDW+YYIERL S IQKI+TIPAALQ V NPVPR +HPDWL K+LLEKND ++Q++I+++FT   +++           V + E S D       D+E+ G     K  H  P AP   K+++V   +  ++    DL  +  W+E+LG PP++GT+++E   W+ FHK+KW LQ  QR A R+ +R    EGV      R  P +GL +F ++ AR+IL+  W+I+Q+SE++  G+F +++++ +DLH I+++IPR+FYVN +  K   GA++RKVN++LPRS    +LY+Y+VPE +++EH +E+ A+LS+PD+EG+YETQVPL  RA++ LGCVC V++ + R L+G + + F L+ LE ++LA  +YLE   ++HIY YH    ++A++ +F+P+ ++ SVFVL+TV+SNQMP+L  LY  E     L +E++G    PP    ++F+VR ETD + + R IQR L AY++E+RGPTL+ +Q+  +     + IP L+ FPLV  P    D      LDWQR  A++ I+ YL ++  L    + +RYFHIP+GN+ P D   + SD+FFARHL R NH+LW+SPT RPDLGGKE D+  LV EFD+  + EIN  GCYSTVCVE+ + +LAVNT+LQSHHV+D EG  S   S D IQQASLE+M+     A+A   SYDE A C+ +F++LK +++ W++E+    N +AD Q++HFYR+LRSP ++L+DPAL + +H +MKK F+QLIAEFK LGS+++YANFN+IIL +KKRRV+DA+AYV+YI +SI SK  F ++ +    CWE+L+WMDP+N+GGI+ K +       + D +K     +   ++D++        +       E  +E NWN+ +FLP +A+CQ +F + ++ +I +VY  + + L+    GSTPV+RRG S   QE        P  + F+Q  + + LT+  F ITQKI K ++G R      E FPVL GSHL L NP+LEFIK VC+VL LD NI NQVNKL RDLL+LV +G+F++EA F+DPC S+++PE+IC  CN CRDLDLC+D   +      P  + C N  CQ  Y+ S +E  LV +L ++ M++TLQDL CLKC+ VK+ +M  +C CAG F        F +Q+ IF NIA+HY MS+L ETL+++
Sbjct:  111 GCEREVSSFLSKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIRLSFHTVEDLVKVRKEISPAVKKNREQDHASDAYTALLSSVLQRGGVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHVAHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMIDGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMVTYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYVGGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLRHALEEEEKVPVEQVTNFEEVCDEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPGANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEKRRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLSAAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNVKKPKVTISYPGAMLNIMVKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQ-----------VTMAEASEDSPRPSAPDMEDFGLV---KLPH--PAAPVTVKRKRV---LWESQEESQDLTPTVPWQEILGQPPALGTSQEEWLVWLRFHKKKWQLQARQRLARRKRQRLESAEGVLRPGAIRDGPATGLGSFLRRTARSILDLPWQIVQISETSQAGLFRLWALVGSDLHCIRLSIPRVFYVNQRVAKAEEGASYRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVHLGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQAHKALFGIFIPSQRRASVFVLDTVRSNQMPSLGALYSAEHG---LLLEKVGPELLPP--PKHTFEVRAETDLKTICRAIQRFLLAYKEERRGPTLIAVQSSWELKRLASEIPVLEEFPLV--PICVADKINYGVLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNL-PEDISTFGSDLFFARHLQRHNHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTILQSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAP-ASYDETALCSNTFRILKSMVVGWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLGSSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKETFHSLTISFSRCWEFLLWMDPSNYGGIKGK-VSSRIHCGLQDSQKAGGAEDEQENEDDEEERDGEEEEEAEESNVEDLLENNWNILQFLPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGAVGALPGMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNPALEFIKYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNFCRDLDLCKDSSFSEDGAVLPQWL-CSN--CQAPYDSSAIEMTLVEVLQKKLMAFTLQDLVCLKCRGVKETSMPVYCSCAGDFALTIHTQVFMEQIGIFRNIAQHYGMSYLLETLEWL 2277